Isotopically Labeled and Unlabeled Reference Standards

 

Custom Synthesis Services

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Our core business is in the small-scale (milligram to gram) synthesis of pharmaceutical active organic compounds for research purposes and use as Certified Analytical Reference Standards. If you can draw it, we can probably synthesize it (at a price of course, that covers our R&D efforts!).

Stable Isotope Labeled (SIL) and Unlabeled Reference Standards

We specialize in small-scale synthesis of:

- APIs
- Metabolites
- Impurities
- Analogues
- Intermediates



With decades of combined experience, we are experts in the synthesis of stable labeled APIs and metabolites. Our extensive experience allows us to place deuteriums in the most stable positions to limit exchange, which ensures the quality of your assay. In cases where deuterium labeling is not desirable, we happily rely on 13C or 15N.

We are a registered DEA lab for Schedules I to V controlled compounds.

 

We have a large number of Anaytical Reference Standards available in stock for delivery. Please view our catalog of high-purity compounds and sealed solutions or request a quote for those listed and for custom-synthesis of those that are not listed in our catalog.

 

Full-time Equivalent (FTE) service is also available for R&D efforts, custom-synthesis of comounds with limited or no literature precedent requiring synthesis method development, or for primarily research oriented projects.

 

Quality Matters

Are you buying poorly characterized and unsupported reference standards? You don't need to settle for TLC or single wavelength purity determination.

With our full chemical certification, you will never need to doubt the authenticity or purity of Chemtos reference standards. Every compound provided by Chemtos comes fully certified with UV Diode Array HPLC purity analysis, proton NMR analysis, LC/MS and all of the supporting data. All analytical work is done under GLP conditions. Concentrations of our single use reference standard solutions in fame sealed ampules are verified by Quantitative proton NMR in order to independently confirm the stated potency/concentration value. See a sample Certificate of Analysis.

Learn more about the Chemtos Difference

N-Boc-Methamphetamine

High purity N-Boc Methamphetamine (Methamphetamine tert-butyl Carbamate) includes a comprehensive Certificate of Analysis and all supporting analytical data

Propoxate oxalate

High purity Propoxate ((R)-Propoxate, Propoxato, Propoxatum, 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid, propyl ester) Oxalate includes a comprehensive Certificate of Analysis and all supporting analytical data

Etodesnitazene (Etazene) 1mg/ml

High purity Etodesnitazene (Etazene) Citrate includes a comprehensive Certificate of Analysis and all supporting analytical data

5-Methyl Etodesnitazene 1mg/ml

High purity 5-Methyl Etodesnitazene Citrate includes a comprehensive Certificate of Analysis and all supporting analytical data

Metodesnitazene (Metazene) 1mg/ml

High purity Metodesnitazene (Metazene) Citrate includes a comprehensive Certificate of Analysis and all supporting analytical data

Methylenedioxynitazene 1mg/ml

High purity Methylenedioxynitazene Citrate includes a comprehensive Certificate of Analysis and all supporting analytical data

Nalmefene-d5

High purity Nalmefene labeled d5 includes a comprehensive Certificate of Analysis and all supporting analytical data

Zelboraf-d7 (Vemurafenib-d7)

High purity Zelboraf Labeled-d7 includes a comprehensive Certificate of Analysis and all supporting analytical data

1-Ethyl-2-fluoropyridin-1-ium Tetrafluoroborate

High purity 1-Ethyl-2-fluoropyridin-1-ium Tetrafluoroborate includes only Proton NMR based Certificate of Analysis - compound is reactive and will react will trace levels of exchangeable protons in solvent including moisture, alcohol and acids. This compound is used for functionalization/derivatization of compounds to increase their Mass Spec Electrospray ionization efficiency

Lansoprazole

High purity Lansoprazole includes a comprehensive Certificate of Analysis and all supporting analytical data

MDMB-CHMICA acid metabolite M2 1mg/ml

High purity MDMB-CHMICA acid metabolite ( AMB-CHMINACA acid metabolite, 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoic acid) solution includes a comprehensive Certificate of Analysis and all supporting analytical data

2C-E HCl (2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine HCl)

High purity 2C-E HCl (2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine HCl) includes a comprehensive Certificate of Analysis and all supporting analytical data